Conception to ongoing pregnancy: the 'black box' of early pregnancy loss

Early pregnancy loss.

Pregnancy is a significant event in a woman’s life, and emotional attachment to the pregnancy and developing baby may begin early in the first trimester. For most women, experiencing a first trimester loss is a difficult and vulnerable time. When it occurs, the grief can be as profound as for any perinatal or other major loss [1]. Spontaneous abortion (a pregnancy that ends spontaneously before...

Endometrial Granulated Lymphocytes in Women Suffering Spontaneous Early Pregnancy Loss

Spontaneous abortion is the most common complication of pregnancy. Several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. Leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (eGL) is the predominant decidual leukocyte population in the first trimester o...

Early Pregnancy Loss Following Laparoscopic Management of Ovarian Abscess Secondary to Oocyte Retrieval

Chapter 2 Early Pregnancy Loss

Pregnancy is a significant event in a woman’s life, and emotional attachment to the pregnancy and developing baby may begin early in the first trimester. For most women, experiencing a first trimester loss is a difficult and vulnerable time. When it occurs, the grief can be as profound as for any perinatal or other major loss [1]. Spontaneous abortion (a pregnancy that ends spontaneously before...

The placenta and adverse pregnancy outcomes – opening the black box?

A healthy placenta is critical for a healthy pregnancy. Conversely, abnormal placental structure and function is seen in conditions which are associated with stillbirth including: fetal growth restriction, preeclampsia, placental abruption and obstetric cholestasis. Abnormalities can be seen ranging from a reduction in placental size in stillbirth to microscopic changes in placental villous arc...